Channel-Dependent Activation of ERK in Paraventricular Thalamus Modulates Acid-Induced Chronic Muscle Pain
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چکیده
Wen-Kwei Chen,1 Ingrid Y Liu,2 Ya-Ting Chang,1,3 Yong-Cyuan Chen,1 Chih-Cheng Chen,1,3 Chen-Tung Yen,3 Hee-Sup Shin,4 and Chien-Chang Chen1,3,5 1Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan, 2Institute of Human Genetics, Tzu Chi University, Hualien 97004, Taiwan, 3Institute of Zoology, National Taiwan University, Taipei 10617, Taiwan, 4Center for Neural Science, Korea Institute of Science and Technology, Seoul 136-791, Korea, and 5Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 11490, Taiwan
منابع مشابه
Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.
Treatments for chronic musculoskeletal pain, such as lower back pain, fibromyalgia, and myofascial pain syndrome, remain inadequate because of our poor understanding of the mechanisms that underlie these conditions. Although T-type Ca2+ channels (T-channels) have been implicated in peripheral and central pain sensory pathways, their role in chronic musculoskeletal pain is still unclear. Here, w...
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تاریخ انتشار 2010